Heat shock protein 70 is a potent activator of the human complement system
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چکیده
منابع مشابه
The production of molecular clones of Toxoplasma gondii-derived heat shock protein 70 kDa
Toxoplasmosis is a common and widespread infection in humans and many other species of warm–blooded animals. Toxoplasma gondii-derived heat shock protein 70 (Hsp70) may play an important role in the virulence of Toxoplasma gondii (T. gondii). In the present study, T. gondii Hsp70 was amplified by polymerase chain reaction (PCR) from the DNA of the T. gondiitachyzoite RH strain through the use o...
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Background: Wet cupping therapy is a complementary therapy in pain management. The mechanism of this therapy, however, needs further elucidation. Cells injured by wet cupping therapy seem to stimulate the expression of heat shock protein 70 (HSP70). Its benefit in pain reduction could be mediated by the expression of ß-endorphin. This study aimed at determining the correlation between HSP70 and...
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Alzheimer's disease (AD) is the most common neurodegenerative disease that caused dementia which has no effective treatment. Growing evidence has demonstrated that AD is a "protein misfolding disorder" that exhibits common features of misfolded, aggregation-prone proteins and selective cell loss in the mature nervous system. Heat shock protein 70 (HSP70) attracts extensive attention worldwide, ...
متن کاملIncreased expression of heat shock protein-binding protein 1 and heat shock protein 70 in human hepatocellular carcinoma tissues.
Heat shock protein-binding protein 1 (HspBP1) is a co-chaperone that inhibits heat shock 70-kDa protein (Hsp70) activity. In mouse neuroblastomas and lung tumors, the protein levels of HspBP1 and Hsp70 are elevated by a similar amount compared to non-tumor tissues. However, no studies have been reported regarding the levels of HspBP1 in human cancer tissues. Our previous proteomic study demonst...
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Introduction: Breast cancer is the most common cancer diagnosed among women worldwide. Increased molecular and genetic information about cancer has improved diagnostic, screening, and treatment methods for cancer. Heat shock protein 70 (HSP70) is overexpressed in breast cancer patients and involved in malignant properties of breast cancer. Due to the noninvasive nature of saliva collection and ...
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ژورنال
عنوان ژورنال: Cell Stress & Chaperones
سال: 2002
ISSN: 1355-8145,1466-1268
DOI: 10.1379/1466-1268(2002)007<0017:hspiap>2.0.co;2